1: 1.) POCl3 / 1.) 1,2-dichloroethane, RT, 30 min, 2.) 1,2-dichloroethane, reflux, 10 h 2: 37 percent / Et3N, pyridine / 1.) 70 deg C, 1 h, 2.) reflux, 3 h 3: mCPBA / CH2Cl2 4: 48 percent / HNO3, Ac2O / 2 h / 0 °C View Scheme

1: 1.) POCl3 / 1.) 1,2-dichloroethane, RT, 30 min, 2.) 1,2-dichloroethane, reflux, 10 h 2: 37 percent / Et3N, pyridine / 1.) 70 deg C, 1 h, 2.) reflux, 3 h View Scheme

1: 1.) POCl3 / 1.) 1,2-dichloroethane, RT, 30 min, 2.) 1,2-dichloroethane, reflux, 10 h 2: 37 percent / Et3N, pyridine / 1.) 70 deg C, 1 h, 2.) reflux, 3 h 3: mCPBA / CH2Cl2 View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '13132411', constants.ctx, '0')">aluminium chloride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1718733', constants.ctx, '0')">ethanol</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br /> <br /> <br /> &nbsp;