雌甾-1,3,5(10)-三烯2,3,17-三醇合成路线 （共 26 条）
反应条件
1: 1.) CCl3F, 2.) Bu4NF / 1.) -78 deg C to 0 deg C, 2.) 25 deg C 2: 12 mg / N-trimethylsilylimidazole / Heating 3: potassium nitrosodisulfonate, KI View Scheme
参考文献
Steroids, , vol. 53, # 6 p. 649 - 661
反应条件
1: NaHSO3, aq. NaOH 2: NaIO4, aq. HCl, AcOH View Scheme
参考文献
Steroids, , vol. 28, # 5 p. 733 - 741
反应条件
cytochrome P450 1A2; NADPH-generating system in phosphate buffer T=37°C; Oxidation; pH=7.4; 0.25 h; Enzyme kinetics; Further Variations:Reagentstime;
参考文献
Chemical Research in Toxicology, , vol. 11, # 6 p. 659 - 665
反应条件
1: K2CO3 2: Al(OiPr)3, cyclohexanone 3: Py*HCl / 200 °C View Scheme
参考文献
Fishman,J. et al.
Journal of Organic Chemistry, 1960 , vol. 25, p. 585 - 588
反应条件
1,4-dithio-DL-threitol; human liver catechol-O-methyltransferase; magnesium chloride in water T=37°C; pH=7.4; 0.5 h; Enzyme kinetics; Further Variations:Reagents;
参考文献
Lambert, Joshua D.; Chen, Dapeng; Wang, Ching Y.; Ai, Ni; Sang, Shengmin; Ho, Chi-Tang; Welsh, William J.; Yang, Chung S.
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 7 p. 2501 - 2507
反应条件
in methanol; diethyl ether T=30°C; Rate constant;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 31, # 9 p. 3309 - 3314
