1: PTAS With tetrabutyl ammonium fluoride in tetrahydrofuran; water T=20°C; 1 h; 2: 2-Chloro-1-trifluoromethylbenzene With 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl; bis(η3-allyl-μ-chloropalladium(II)) in tetrahydrofuran; water T=80°C; 3 h;
1: sodium tetraphenyl borate With Amberlite(R)IRA-900 resin in water 2: 1-iodo-2-(trifluoromethyl)benzene With palladium diacetate in N,N-dimethyl-formamide T=80°C; Suzuki-Miyaura coupling reaction; 6 h; Further stages.;