反应条件
1: bromine / aq. acetate buffer / 24 h / 20 °C / pH 4 / |Darkness
2: Na2[PdCl4]; sodium carbonate; triphenylphosphine-3,3',3''-trisulfonic acid trisodium salt / water; acetonitrile / 1 h / 80 °C
3: trifluoroacetic acid / water / 1 h / 20 °C
View Scheme
参考文献
Moreau, Christelle; Kirchberger, Tanja; Swarbrick, Joanna M.; Bartlett, Stephen J.; Fliegert, Ralf; Yorgan, Timur; Bauche, Andreas; Harneit, Angelika; Guse, Andreas H.; Potter, Barry V. L.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 24 p. 10079 - 10102