1,3-苯并噻唑-6-羧酸合成路线 （共 14 条）
反应条件
potassium permanganate
参考文献
Zhurnal Obshchei Khimii, , vol. 20, p. 1191,1195; engl. Ausg. S. 1235, 1239
参考文献
Journal of the Chemical Society, , p. 355,361
反应条件
(i) aq. Na2S, (ii) aq. HCO2H, Zn; Multistep reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 11, # 2 p. 270 - 273
反应条件
1: zinc 2: KMnO4 View Scheme
参考文献
Zhurnal Obshchei Khimii, , vol. 20, p. 1191,1195; engl. Ausg. S. 1235, 1239
参考文献
Costanzo; Michael J.; Maryanoff; Bruce E.
Patent: US5523308 A1, 1996 ;
US 5523308 A
参考文献
American Home Products
Patent: US6344451 B1, 2002 ;
Location in patent: Page column 9 ;
US 6344451 B1
反应条件
N,N-dimethyl-formamide in dichloromethane
参考文献
Wyeth
Patent: EP1149104 B1, 2002 ;
反应条件
1: 1,3-benzothiazole-6-carboxylic acid With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; 2: methyl iodide in tetrahydrofuran; hexane T=20°C;
参考文献
SCHERING CORPORATION
Patent: WO2008/82490 A2, 2008 ;
Location in patent: Page/Page column 102; 103 ;
WO 2008/082490 A2
参考文献
US5523308 A1, ;
US 5523308 A
反应条件
1: SOCl2 2: aqueous NH3 View Scheme
参考文献
Fridman
Zhurnal Obshchei Khimii, 1950 , vol. 20, p. 1191,1195; engl. Ausg. S. 1235, 1239
