乙基2-[2-[二(2-乙氧基-2-氧代乙基)氨基]乙基-(2-乙氧基-2-氧代乙基)氨基]乙酸酯合成路线 （共 4 条）
反应条件
1: With sulfuric acid T=90°C; 17 h; Inert atmosphere; 2: With sodium hydrogencarbonate in water pH=9;
参考文献
GE HEALTHCARE BIO-SCIENCES AB; ALGOTSSON, Mattias; ANDERSSON, Lars, C.; BREKKAN, Eggert; HEDEMYR, Lee; MALOISEL, Jean-Luc; PALMGREN, Ronnie
Patent: WO2011/152782 A1, 2011 ;
Location in patent: Page/Page column 15 ;
反应条件
sulfuric acid; sodium hydrogencarbonate 1.) EtOH, reflux, 24 h, 2.) EtOH, H2O; Yield given. Multistep reaction;
参考文献
Taylor, John S.; Schultz, Peter G.; Dervan, Peter B.
Tetrahedron, 1984 , vol. 40, # 3 p. 457 - 465
参考文献
Yaroshenko,G.F. et al.
Zhurnal Organicheskoi Khimii, 1974 , vol. 10, # 3 p. 457 - 460,462 - 464
反应条件
sodium hydroxide; hydrogen sulfide in water
参考文献
Taylor, John S.; Schultz, Peter G.; Dervan, Peter B.
Tetrahedron, 1984 , vol. 40, # 3 p. 457 - 465
