3-[4-(三氟甲基)苯基]-1H-吡唑合成路线 (共 3 条)
反应条件
1: NaH / tetrahydrofuran / 0 - 20 °C 2: hydrazine / methanol View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 15 p. 3540 - 3546
反应条件
hydrazine in methanol
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 15 p. 3540 - 3546
反应条件
1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / 1,4-dioxane / 2 h / 20 °C / Inert atmosphere 2: hydrazine monohydrochloride; water; toluene-4-sulfonic acid / 1,4-dioxane / 0.25 h / 80 °C / Inert atmosphere View Scheme
参考文献
Molecules, , vol. 16, # 11 p. 9340 - 9356