4-氰基-N-甲基苯甲酰胺合成路线 （共 8 条）
反应条件
N,N,N',N'-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a;2',1'-c][1,4] diazepine-2,12-diamine in N,N-dimethyl-formamide T=20°C;
参考文献
Cutulic, Sylvain P. Y.; Murphy, John A.; Farwaha, Hardeep; Zhou, Sheng-Ze; Chrystal, Ewan
Synlett, 2008 , # 14 p. 2132 - 2136
参考文献
Street, Leslie J.; Baker, Raymond; Castro, Jose L.; Chambers, Mark S.; Guiblin, Alexander R.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 11 p. 1529 - 1538
反应条件
sodium carbonate in methanol 7 h; Irradiation;
参考文献
Kikugawa; Fu; Sakamoto
Synthetic Communications, 1993 , vol. 23, # 8 p. 1061 - 1069
反应条件
1: 80 percent / Et3N, PPh3-CBr4 / acetonitrile / 3 h / Heating 2: 89 percent / 10percent aq. HBr / dioxane / 11 h / Heating 3: SOCl2 / 2 h / Heating 4: 84 percent / H2O; benzene 5: 85 percent / Na2CO3 / methanol / 7 h / Irradiation View Scheme
参考文献
Kikugawa; Fu; Sakamoto
Synthetic Communications, 1993 , vol. 23, # 8 p. 1061 - 1069
反应条件
1: 89 percent / 10percent aq. HBr / dioxane / 11 h / Heating 2: SOCl2 / 2 h / Heating 3: 84 percent / H2O; benzene 4: 85 percent / Na2CO3 / methanol / 7 h / Irradiation View Scheme
参考文献
Kikugawa; Fu; Sakamoto
Synthetic Communications, 1993 , vol. 23, # 8 p. 1061 - 1069
反应条件
1: SOCl2 / 2 h / Heating 2: 84 percent / H2O; benzene 3: 85 percent / Na2CO3 / methanol / 7 h / Irradiation View Scheme
参考文献
Kikugawa; Fu; Sakamoto
Synthetic Communications, 1993 , vol. 23, # 8 p. 1061 - 1069
反应条件
1: thionyl chloride / dichloromethane; N,N-dimethyl-formamide / 3 h / 60 °C / |Inert atmosphere; |Schlenk technique 2: triethylamine / diethyl ether; methanol / 1 h / 20 °C / |Inert atmosphere; |Schlenk technique View Scheme
参考文献
Tang, Qiuzheng; Xia, Dexin; Jin, Xiqing; Zhang, Qing; Sun, Xiao-Qiang; Wang, Congyang
Journal of the American Chemical Society, 2013 , vol. 135, # 12 p. 4628 - 4631
参考文献
Salfetnikova; Vasil'ev; Rudenko
Russian Journal of Organic Chemistry, 1998 , vol. 34, # 6 p. 838 - 844
