4-氨基甲基-1-叔丁氧羰基哌啶-4-甲酸甲酯合成路线 (共 6 条)
反应条件
hydrogen; platinum(IV) oxide in ethyl acetate P=2585.81 Torr; 2 h;
参考文献
Duan, Jingwu; King, Bryan W.; Decicco, Carl; Maduskuie JR., Thomas P.; Voss, Mathew E.
Patent: US2004/72802 A1, 2004 ;
Location in patent: Page/Page column 47 ;
反应条件
1: NaH / tetrahydrofuran 2: H2; aq. HCl / PtO2 / methanol View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 10 p. 2699 - 2704
反应条件
1: triethylamine / dichloromethane / 0 - 20 °C 2: lithium diisopropyl amide / tetrahydrofuran / -78 - 20 °C 3: methanol / 20 °C 4: platinum(IV) oxide; hydrogen / acetic acid / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 19 p. 5910 - 5915
反应条件
1: methanol / 20 °C 2: platinum(IV) oxide; hydrogen / acetic acid / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 19 p. 5910 - 5915
反应条件
1: triethylamine / dichloromethane / 0 - 20 °C 2: lithium diisopropyl amide / tetrahydrofuran / -78 - 20 °C 3: methanol / 20 °C 4: platinum(IV) oxide; hydrogen / acetic acid / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 19 p. 5910 - 5915
反应条件
1: lithium diisopropyl amide / tetrahydrofuran / -78 - 20 °C 2: methanol / 20 °C 3: platinum(IV) oxide; hydrogen / acetic acid / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 19 p. 5910 - 5915