环戊烯-1,3-溴-(7CI,9CI)合成路线 （共 17 条）
参考文献
Piotrowska,H. et al.
Bulletin de l'Academie Polonaise des Sciences, Serie des Sciences Chimiques, 1971 , vol. 19, p. 595 - 598
反应条件
in toluene
T=80°C; 2 h;
参考文献
Leo, Edgar A.; Delgado, Julio; Domingo, Luis R.; Espinos, Amparo; Miranda, Miguel A.; Tormos, Rosa
Journal of Organic Chemistry, 2003 , vol. 68, # 25 p. 9643 - 9647
反应条件
1: 1) lithium diisopropylamide / 1) THF, -78 deg C, 30 min, 2) HMPT, 25 deg C
2: methanol / 18 h / 25 °C
3: 1,5-diazabicyclo<4.3.0>non-5-ene / benzene / Heating
View Scheme
参考文献
Yu, Lin-Chen; Helquist, Paul
Journal of Organic Chemistry, 1981 , vol. 46, # 22 p. 4536 - 4541
反应条件
1: DIBAL-H / hexamethylphosphoric acid triamide; tetrahydrofuran / 1.) 0 deg C, 1 h; 2.) 25 deg C, 16 h
2: NaOH / H2O; ethanol / 1 h / Heating
3: benzoquinone, MnO2 / Pd(OAc)2 / tetrahydrofuran
View Scheme
参考文献
Yu, Lin-Chen; Helquist, Paul
Journal of Organic Chemistry, 1981 , vol. 46, # 22 p. 4536 - 4541
反应条件
(i) Mg, Et2O, (ii) /BRN= 2234703/; Multistep reaction;
参考文献
Hueckel,W.; Bross,R.
Justus Liebigs Annalen der Chemie, 1963 , vol. 664, p. 1 - 18
反应条件
ammonium chloride; zinc in tetrahydrofuran; water
appropriate alkyltin chloride is added to THF/H2O mixt. with excess of zinc powder, appropriate allyl bromide is added dropwise under stirring within 5 min, mixt. is stirred for 30 min; extn. (petroleum ether), separated org. layer is washed (aq. NaCl), drying (MgSO4), solvent is removed, distn.;
参考文献
Gyldenfeldt, Friederike von; Marton, Daniele; Tagliavini, Giuseppe
Organometallics, 1994 , vol. 13, p. 906 - 913
反应条件
1.1: Mg / tetrahydrofuran
1.2: 94 percent / tetrahydrofuran / 3 h / 20 °C
2.1: 68 percent / 2N H2SO4 / acetonitrile; H2O / 20 h / 20 °C
View Scheme
参考文献
Ali Dondas; Grigg, Ronald; Thibault, Sylvie
Tetrahedron, 2001 , vol. 57, # 32 p. 7035 - 7045
