3,5-二氟-4-甲氧基苯胺合成路线 （共 13 条）
反应条件
trifluorormethanesulfonic acid; fluorine T=20°C; Title compound not separated from byproducts;
参考文献
Journal of Fluorine Chemistry, , vol. 126, # 4 p. 661 - 667
反应条件
1: 64 percent / I2, aq. NaHCO3 / Ambient temperature 2: 1.) aq. NaNO2, H2SO4, 2.) Cu / 1.) 0 deg C, 30 min, 2.) EtOH, from 60 deg C to 75 deg C, 3 h 3: 83 percent / dimethylformamide / 22 h / 120 - 140 °C View Scheme
参考文献
Qiu, Jian; Stevenson, Scott H.; O'Beirne, Michael J.; Silverman, Richard B.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 2 p. 329 - 332
反应条件
sulfuric acid; copper(II) sulfate; xylene
Diazotization;
参考文献
Niemann; Benson; Mead
Journal of the American Chemical Society, 1941 , vol. 63, p. 2204,2208
