potassium fluoride; trimethylamine in N,N-dimethyl-formamide 14 h; Ambient temperature;

1: 87.4 percent / pyridine; dimethylformamide / 3.75 h / 75 °C 2: 85 percent / Et4NCl, phosphoryl chloride, N,N-dimethylaniline / acetonitrile / 1.) room temperature; 2.) 100 deg C, 10 min 3: 93 percent / KF, Me3N / dimethylformamide / 14 h / Ambient temperature View Scheme

1: 85 percent / Et4NCl, phosphoryl chloride, N,N-dimethylaniline / acetonitrile / 1.) room temperature; 2.) 100 deg C, 10 min 2: 93 percent / KF, Me3N / dimethylformamide / 14 h / Ambient temperature View Scheme

1: 66 percent / HF (60percent), tert-butyl nitrite (TBN) / pyridine / 0.02 h / -30 °C 2: 85 percent / 1,2-dimethoxy-ethane / 0.25 h / Ambient temperature View Scheme