Dess-Martin periodane in dichloromethane T=20°C; Dess-Martin oxidation; 12 h;

in dimethyl sulfoxide T=37°C; 72 h; Pseudomonas aeruginosa, culture broth from bouillon powder;

1: 10 percent / NaH / dimethylformamide / 12 h / 20 °C 2: 67 percent / H2SO4 / H2O; tetrahydrofuran / 2 h / 20 °C 3: 77 percent / Dess-Martin periodinane / CH2Cl2 / 12 h / 20 °C View Scheme

1: 73 percent / m-CPBA; K2CO3 / CH2Cl2 / 24 h / 0 °C 2: 10 percent / NaH / dimethylformamide / 12 h / 20 °C 3: 67 percent / H2SO4 / H2O; tetrahydrofuran / 2 h / 20 °C 4: 77 percent / Dess-Martin periodinane / CH2Cl2 / 12 h / 20 °C View Scheme

in water T=27°C; 24 h; biotransformation with Norcadia alba DSM 43130, culture medium: glucose, meat extract, cornsteep solid, peptone, pH 7.4; other bacteria; Product distribution;