DL-3-氨基-3-苯基丙酸合成路线 （共 124 条）
反应条件
1: 75 percent / H2O; acetone
2: 35 percent / NaHCO3 / penicillin acylase / H2O
View Scheme
参考文献
Soloshonok; Fokina; Rybakova; Shishkina; Galushko; Sorochinsky; Kukhar; Savchenko; Svedas
Tetrahedron Asymmetry, 1995 , vol. 6, # 7 p. 1601 - 1610
反应条件
triethylamine in water; acetone
1.) -5 deg C, 2 h, 2.) room temp., 3 h;
参考文献
Cardillo, Giuliana; Gentilucci, Luca; Melchiorre, Paolo; Spampinato, Santi
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 24 p. 2755 - 2758
参考文献
Schulz; Sprung; Kroning
Pharmazie, 1983 , vol. 38, # 5 p. 310 - 313
参考文献
Schulz; Sprung; Kroning
Pharmazie, 1983 , vol. 38, # 5 p. 310 - 313
参考文献
Schulz; Sprung; Kroning
Pharmazie, 1983 , vol. 38, # 5 p. 310 - 313
参考文献
Schulz; Sprung; Kroning
Pharmazie, 1983 , vol. 38, # 5 p. 310 - 313
参考文献
Schulz; Sprung; Kroning
Pharmazie, 1983 , vol. 38, # 5 p. 310 - 313
反应条件
thionyl chloride
3 h; Heating;
参考文献
Adriaenssens, Louis V.; Hartley, Richard C.
Journal of Organic Chemistry, 2007 , vol. 72, # 26 p. 10287 - 10290
反应条件
hydrogenchloride in methanol
T=20°C;
参考文献
Laurent, Sophie; Elst, Luce Vander; Vroman, Antoine; Muller, Robert N.
Helvetica Chimica Acta, 2007 , vol. 90, # 3 p. 562 - 573
反应条件
2: beim Erhitzen ueber den Schmelzpunkt
View Scheme
参考文献
Posner
Chemische Berichte, 1905 , vol. 38, p. 2316
Justus Liebigs Annalen der Chemie, 1912 , vol. 389, p. 35,109
