DL-3-氨基-3-苯基丙酸合成路线 （共 124 条）
反应条件
1: 74 percent / LiAlH4 / tetrahydrofuran / 8 h / 80 - 85 °C 2: 5N HCl / 24 h / 25 °C View Scheme
参考文献
Tetrahedron, , vol. 50, # 27 p. 8099 - 8102
反应条件
1: 82 percent / Zn-Cu / tetrahydrofuran / Heating 2: 76 percent / TFA / 2 h / 20 °C 3: sodium, naphthalene / 1,2-dimethoxy-ethane View Scheme
参考文献
Tetrahedron, , vol. 49, # 48 p. 11329 - 11340
反应条件
1: 86 percent / Zn / tetrahydrofuran / Heating 2: 76 percent / pyridine; H2O / 15 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 49, # 48 p. 11329 - 11340
反应条件
1: 86 percent / Zn-Cu / tetrahydrofuran / Heating 2: 1.) TFA, 2.) sodium, naphthalene / 1.) 20 deg C, 2 h, 2.) DME, 0 deg C View Scheme
参考文献
Tetrahedron, , vol. 49, # 48 p. 11329 - 11340
反应条件
1: 76 percent / TFA / 2 h / 20 °C 2: sodium, naphthalene / 1,2-dimethoxy-ethane View Scheme
参考文献
Tetrahedron, , vol. 49, # 48 p. 11329 - 11340
反应条件
1: (hydrolysis) 2: H2 / Pd-C View Scheme
参考文献
Doklady Chemistry, , vol. 172, p. 103 - 106
Doklady Akademii Nauk SSSR, , vol. 172, # 4 p. 845 - 848
参考文献
Romanova; Rybalko; Tallo; Zyk; Svedas
Russian Journal of Organic Chemistry, 2012 , vol. 48, # 6 p. 860 - 863
反应条件
ammonia; palladium T=10 - 15°C; Hydrogenation; inactive β-oxy-β-phenyl-propionic acid;
参考文献
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 148, p. 311
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 170, p. 187,195
反应条件
malonic acid in ethanol Rodionow-Johnson;
参考文献
Pharmacy and Pharmacology Communications, , vol. 5, # 3 p. 217 - 223
参考文献
US2013/53402 A1, ;
Paragraph 0263 ;
