N-(2-氯乙基)吗啉盐酸盐合成路线

参考文献

Goldstein, David M.; Alfredson, Tom; Bertrand, Jay; Browner, Michelle F.; Clifford, Ken; Dalrymple, Stacie A.; Dunn, James; Freire-Moar, Jose; Harris, Seth; Labadie, Sharada S.; La Fargue, JoAnn; Lapierre, Jean Marc; Larrabee, Susan; Li, Fujun; Papp, Eva; McWeeney, Daniel; Ramesha, Chakk; Roberts, Rick; Rotstein, David; San Pablo, Bong; Sjogren, Eric B.; So, On-Yee; Talamas, Francisco X.; Tao, Will; Trejo, Alejandra; Villasenor, Armando; Welch, Mary; Welch, Teresa; Weller, Paul; Whiteley, Phyllis E.; Young, Kelly; Zipfel, Sheila
Journal of Medicinal Chemistry, 2006 , vol. 49, # 5 p. 1562 - 1575

3647-69-6N-(2-氯乙基)吗啉盐酸盐+

100-83-4间羟基苯甲醛

81068-26-03-(2-吗啉-4-乙氧基)苯甲醛

参考文献

CEPHALON, INC.; BRESLIN, Henry J.; CURRY, Matthew A.; GINGRICH, Diane E.; LEARN, Keith S.; OTT, Gregory R.; WAGNER, Jason C.
Patent: WO2013/116291 A1, 2013 ;
Location in patent: Page/Page column 220 ;

3647-69-6N-(2-氯乙基)吗啉盐酸盐+

584-08-7碳酸钾+

100-83-4间羟基苯甲醛

81068-26-03-(2-吗啉-4-乙氧基)苯甲醛

参考文献

Sanofi
Patent: US5736548 A1, 1998 ;

269410-08-44-吡唑硼酸频哪醇酯+

3647-69-6N-(2-氯乙基)吗啉盐酸盐

864754-18-71-(2-吗啉乙基)-1H-吡唑-4-硼酸频那醇酯

参考文献

WO2010/75270 A1, ;

Page/Page column 160 ;
WO 2010/075270 A1

3647-69-6N-(2-氯乙基)吗啉盐酸盐

285983-48-41-[2-(4-甲基苯基)-5-叔丁基吡唑-3-基]-3-[4-(2-吗啉-4-基乙氧基)萘-1-基]脲

参考文献

TORAY INDUSTRIES, INC.
Patent: US2012/184735 A1, 2012 ;

3647-69-6N-(2-氯乙基)吗啉盐酸盐+

123-08-0对羟基苯甲醛

82625-45-44-(2-吗啉乙氧基)苯甲醛

参考文献

CELGENE CORPORATION; GANDHI, Anita; DIMARTINO, Jorge; CHOPRA, Rajesh
Patent: WO2014/39960 A1, 2014 ;
Location in patent: Page/Page column 66 ;

3647-69-6N-(2-氯乙基)吗啉盐酸盐+

123-30-8对氨基苯酚

52481-41-14-(2-吗啉-4-乙氧基)苯胺

参考文献

NOVARTIS AG; NOVARTIS PHARMA GmbH
Patent: WO2007/71752 A2, 2007 ;
Location in patent: Page/Page column 68 ;
WO 2007/071752 A2

3647-69-6N-(2-氯乙基)吗啉盐酸盐

52481-41-14-(2-吗啉-4-乙氧基)苯胺

参考文献

Pan, Xiaoyan; Wang, Fang; Zhang, Yanmin; Gao, Hongping; Hu, Zhigang; Wang, Sicen; Zhang, Jie
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 9 p. 2527 - 2534

3647-69-6N-(2-氯乙基)吗啉盐酸盐

64039-56-12-(2-吗啉-4-基乙氧基)苯胺

参考文献

Mao, Ming-Zhen; Li, Yu-Xin; Zhou, Yun-Yun; Chen, Wei; Liu, Tuan-Wei; Yu, Shu-Jing; Wang, Su-Hua; Li, Zheng-Ming
Chemical Biology and Drug Design, 2011 , vol. 78, # 4 p. 695 - 699

100-02-7对硝基苯酚+

3647-69-6N-(2-氯乙基)吗啉盐酸盐

65300-53-04-(2-(4-硝基苯氧基)乙基)吗啉

参考文献

Pan, Xiaoyan; Dong, Jinyun; Gao, Hongping; Wang, Fang; Zhang, Yanmin; Wang, Sicen; Zhang, Jie
Chemical Biology and Drug Design, 2014 , vol. 83, # 5 p. 592 - 599