您好，欢迎来到魔法化学网！
合作交流
|
服务时间(9:30-18:00)
百科
百科
▼
百科
资讯
搜索
结构式
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
首页
化合物百科
价格行情
资讯
化工导航
实验室工具
搜索
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
盐酸甲状旁腺激素
合成路线
（共 46 条）
1093944-40-1
→
反应条件
364782-34-3
盐酸甲状旁腺激素
反应条件
hydrogen; palladium on activated carbon in water; isopropyl alcohol T=20°C; 3 h;
参考文献
Dipharma Francis S.r.l.
Patent: EP2022777 A2, 2009 ;
Location in patent: Page/Page column 6 ;
1240705-66-1
→
反应条件
364782-34-3
盐酸甲状旁腺激素
反应条件
hydrogen; palladium dichloride in methanol; ethyl acetate T=20°C; P=750.075 Torr; 0.5 h; Product distribution / selectivity;
参考文献
ZACH SYSTEM S.P.A.; CATOZZI, Nicola; COTARCA, Livius; FOLETTO, Johnny; FORCATO, Massimiliano; GIOVANETTI, Roberto; SORIATO, Giorgio; VERZINI, Massimo
Patent: WO2010/94674 A2, 2010 ;
Location in patent: Page/Page column 28 ;
1273259-52-1
→
反应条件
364782-34-3
盐酸甲状旁腺激素
反应条件
1: With sodium hydrogencarbonate in water; toluene T=15 - 20°C; pH=8 - 9; Inert atmosphere; 2: With hydrogen; 5 Pd(II)/C(eggshell) in methanol; toluene T=20°C; P=750.075 Torr; Product distribution / selectivity;
参考文献
ZACH SYSTEM S.P.A.; CATOZZI, Nicola; COTARCA, Livius; FOLETTO, Johnny; FORCATO, Massimiliano; GIOVANETTI, Roberto; SORIATO, Giorgio; VERZINI, Massimo
Patent: WO2011/29833 A1, 2011 ;
Location in patent: Page/Page column 23-24 ;
→
反应条件
364782-34-3
盐酸甲状旁腺激素
反应条件
1: With Et3N-BH3 in methanol T=20°C; 16 h; 2: With hydrogenchloride in water T=0°C; 13 h; Reagent/catalyst;
参考文献
Barniol-Xicota, Marta; Turcu, Andreea L.; Codony, Sandra; Escolano, Carmen; Vazquez, Santiago
Tetrahedron Letters, 2014 , vol. 55, # 15 p. 2548 - 2550
226256-56-0
西那卡塞
→
反应条件
364782-34-3
盐酸甲状旁腺激素
反应条件
hydrogenchloride in n-heptane; water; toluene T=25 - 30°C; pH=1 - 2; Product distribution / selectivity;
参考文献
Amneal Pharmaceuticals, LLC
Patent: US2011/319663 A1, 2011 ;
Location in patent: Page/Page column 18 ;
1005450-55-4
(R)-N-(1-(萘-1-基)乙基)-3-(3-(三氟甲基)苯基)丙酰胺
→
反应条件
364782-34-3
盐酸甲状旁腺激素
反应条件
1: With sodium tetrahydroborate; iodine in tetrahydrofuran T=0 - 75°C; 6.5 h; 2: With hydrogenchloride in hexane; water 1 h;
参考文献
MACLEODS PHARMACEUTICALS LIMITED
Patent: WO2008/117299 A1, 2008 ;
Location in patent: Page/Page column 17-18 ;
1207533-91-2
→
反应条件
364782-34-3
盐酸甲状旁腺激素
反应条件
palladium on activated charcoal; hydrogen in water; ethyl acetate T=25 - 30°C; Large scale;
参考文献
Tewari, Neera; Maheshwari, Nitin; Medhane, Roshan; Nizar, Hashim; Prasad, Mohan
Organic Process Research and Development, 2012 , vol. 16, # 9 p. 1566 - 1568
3886-70-2
(R)-1-(1-萘基)乙胺
+
78573-45-2
3-(3-三氟甲基苯基)丙醇
→
反应条件
364782-34-3
盐酸甲状旁腺激素
反应条件
1: With [{(η5-C5Me5)IrCl}2(μ-Cl)2] in toluene T=110°C; 6 h; Inert atmosphere; 2: With hydrogenchloride in diethyl ether; hexane; ethyl acetate; toluene Reagent/catalystTime;
参考文献
ZENTIVA, K.S.; VLASAKOVA Ruzena; HAJICEK Josef
Patent: WO2013/75679 A1, 2013 ;
Location in patent: Page/Page column 9 ;
1204313-93-8
→
反应条件
364782-34-3
盐酸甲状旁腺激素
反应条件
1: With potassium carbonate; thiophenol; N-benzyl-N,N,N-triethylammonium chloride in dimethyl sulfoxide T=25 - 35°C; 24 h; 2: With hydrogenchloride in ethyl acetate T=0 - 25°C;
参考文献
WO2010/4588 A2, ;
Page/Page column 44 ;
129254-76-8
1-(3-溴丙基)-3-(三氟甲基)苯
+
3886-70-2
(R)-1-(1-萘基)乙胺
+
100-52-7
苯甲醛
→
反应条件
364782-34-3
盐酸甲状旁腺激素
反应条件
1: (R)-(+)-1-(1-naphthyl)-ethylamine; benzaldehyde T=25 - 30°C; 2: 1-(3-bromopropyl)-3-(trifluoromethyl)benzene in 1-methyl-pyrrolidin-2-one T=130 - 140°C; 12 h; 3: With hydrogenchloride; water in 1-methyl-pyrrolidin-2-one; toluene pH=0.5 - 2;
参考文献
Amneal Pharmaceuticals, LLC
Patent: US2011/319663 A1, 2011 ;
Location in patent: Page/Page column 18 ;
1
2
3
4
5
下一页
末页
到第
页
确定
