4-[(6-溴吡啶-3-基)甲基]吗啉合成路线 (共 2 条)
反应条件
1: With sodium tris(acetoxy)borohydride; acetic acid in 1,2-dichloro-ethane
T=20°C; 0.666667 h;
2: With sodium hydrogencarbonate in 1,2-dichloro-ethane
参考文献
LOCUS PHARMACEUTICALS, INC.
Patent: US2010/41642 A1, 2010 ;
Location in patent: Page/Page column 20 ;
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran
T=20°C; 1 h;
参考文献
IRM LLC
Patent: WO2008/8747 A1, 2008 ;
Location in patent: Page/Page column 35, 36, 63 ;
WO 2008/008747 A1