N-(2,3,4-三氟苯)乙酰苯胺合成路线 （共 3 条）
反应条件
sulfuric acid; potassium nitrate Ambient temperature;
参考文献
Keana; Kher; Sui Xiong Cai; Dinsmore; Glenn; Guastella; Huang; Ilyin; Lu; Mouser; Woodward; Weber
Journal of Medicinal Chemistry, 1995 , vol. 38, # 22 p. 4367 - 4379
反应条件
KNO3; sulfuric acid in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; ethyl acetate
参考文献
State of Oregon, acting by and through the Oregon State Board of Higher Education, acting for and on behalf of the Oregon Health Sciences University and the University of Oregon, Eugene Oregon; Acea Pharmaceuticals, Inc.; The Regents of the University of California
Patent: US5631373 A1, 1997 ;
反应条件
1: 48 percent / concd. H2SO4, KNO3 / Ambient temperature
2: SnCl2*H2O / ethyl acetate; ethanol / 0.58 h / 70 °C
View Scheme
参考文献
Keana; Kher; Sui Xiong Cai; Dinsmore; Glenn; Guastella; Huang; Ilyin; Lu; Mouser; Woodward; Weber
Journal of Medicinal Chemistry, 1995 , vol. 38, # 22 p. 4367 - 4379
