6-氯-2-(4-氯苯基)-N,N-二甲基咪唑并[1,2-a]吡啶-3-甲胺合成路线 （共 3 条）
反应条件
acetic acid in water T=50 - 55°C; 4 h;
参考文献
Lange; Karolak-Wojciechowska; Wejroch; Rump
Acta Poloniae Pharmaceutica - Drug Research, 2001 , vol. 58, # 1 p. 43 - 52
反应条件
1: [6-chloro-2-(4-chlorophenyl)-imidazo[1,2-a]pyridin-3-ylmethyl]-dimethylamine With methyl iodide in dichloromethane T=20°C; 24 h; 2: potassium cyanide in water 4 h; Heating;
参考文献
Lange; Karolak-Wojciechowska; Wejroch; Rump
Acta Poloniae Pharmaceutica - Drug Research, 2001 , vol. 58, # 1 p. 43 - 52
反应条件
1.1: MeI / CH2Cl2 / 24 h / 20 °C 1.2: H2O / 4 h / Heating 2.1: 85 percent / aq. KOH / ethanol / 8 h / Heating View Scheme
参考文献
Lange; Karolak-Wojciechowska; Wejroch; Rump
Acta Poloniae Pharmaceutica - Drug Research, 2001 , vol. 58, # 1 p. 43 - 52
