1,3,5-三氯-2-氟-苯合成路线 （共 4 条）
反应条件
N-methylhexamethylenetetrammonium fluoride in dimethyl sulfoxide
T=100°C; 0.5 h;
参考文献
Clark, James H.; Nightingale, David J.
Journal of Fluorine Chemistry, 1996 , vol. 78, # 1 p. 91 - 93
反应条件
pyridine; hydrogen fluoride; sodium nitrite
1.) 20 deg C, 10 min, 2.) irradiated, 20 deg C, 18 h; Yield given. Multistep reaction;
参考文献
Yoneda, Norihiko; Fukuhara, Tsuyoshi; Kikuchi, Tetsuo; Suzuki, Akira
Synthetic Communications, 1989 , vol. 19, # 5and6 p. 865 - 872
反应条件
boron tribromide; potassium carbonate
1.) DMF, reflux, 8 h, 2.) CH2Cl2; Yield given. Multistep reaction;
参考文献
Humppi
Synthesis, 1985 , vol. NO. 10, p. 919 - 924
反应条件
1: HNO3
2: Cl2 / 200 °C
3: NaSH, Py
View Scheme
参考文献
Kobrina,L.S.; Yakobson,G.G.
J. Gen. Chem. USSR (Engl. Transl.), 1965 , vol. 35, # 11 p. 2055 - 2062,2046 - 2052
