3-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-1-[三s(1-甲基乙基)甲硅烷基]-1H-吡咯合成路线 （共 14 条）
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; triethylamine; dichloro bis(acetonitrile) palladium(II) in toluene T=90°C; 18 h;
参考文献
Billingsley, Kelvin; Buchwald, Stephen L.
Journal of the American Chemical Society, 2007 , vol. 129, # 11 p. 3358 - 3366
反应条件
1: 1-(Triisopropylsilyl)pyrrole With 2,6-dimethylpyridine; AlCl3, aluminium chloride; boron trichloride in n-heptane; dichloromethane T=20°C; 14 h; Inert atmosphere; 2: 2,3-dimethylbutane-2,3-diol With triethylamine in n-heptane; dichloromethane T=20°C; 0.5 h; Inert atmosphere;
参考文献
THE UNIVERSITY OF MANCHESTER; INGLESON, Michael James
Patent: WO2012/25760 A1, 2012 ;
Location in patent: Page/Page column 57 ;
反应条件
triethylamine in dichloromethane 3 h;
参考文献
THE UNIVERSITY OF MANCHESTER; INGLESON, Michael James
Patent: WO2012/25760 A1, 2012 ;
Location in patent: Page/Page column 35 ;
反应条件
di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium; 4,4'-di-tert-butyl-2,2'-dipyridyl in octane T=80°C; 16 h;
参考文献
Takagi, Jun; Sato, Kazuaki; Hartwig, John F; Ishiyama, Tatsuo; Miyaura, Norio
Tetrahedron Letters, 2002 , vol. 43, # 32 p. 5649 - 5651
反应条件
1: N-bromosuccinimide / acetonitrile 2: 85 percent / Et3N; 2-dicyclohexylphosphino-2',6'-dimethoxybiphenyl / PdCl2(CH3CN)2 / toluene / 18 h / 90 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 45, # 21 p. 3484 - 3488
反应条件
Cp*Rh(η4-C6Me6) in cyclohexane T=150°C; 41 h;
参考文献
Tse; Cho; Smith 3rd.
Organic letters, 2001 , vol. 3, # 18 p. 2831 - 2833
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; dichloro bis(acetonitrile) palladium(II); triethylamine in toluene T=20 - 90°C; Inert atmosphere;
参考文献
Morrison, Matthew D.; Hanthorn, Jason J.; Pratt, Derek A.
Organic Letters, 2009 , vol. 11, # 5 p. 1051 - 1054
反应条件
1: tetrahydrofuran 2: N-bromosuccinimide / acetonitrile 3: 85 percent / Et3N; 2-dicyclohexylphosphino-2',6'-dimethoxybiphenyl / PdCl2(CH3CN)2 / toluene / 18 h / 90 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 45, # 21 p. 3484 - 3488
反应条件
CH3CH2CH2CH2Li in tetrahydrofuran treatment of pyrrole deriv. with butyllithium in THF at -78°C, addn. of borolane deriv.;
参考文献
Ayats, Carles; Soley, Roger; Albericio, Fernando; Alvarez, Mercedes
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 5 p. 860 - 862
反应条件
triethylamine T=20°C; 0.5 h;
参考文献
Del Grosso, Alessandro; Helm, Matthew D.; Solomon, Sophia A.; Caras-Quintero, Dolores; Ingleson, Michael J.
Chemical Communications, 2011 , vol. 47, # 46 p. 12459 - 12461
