(3E)-3-羟基亚胺-2,2-二甲基丙烷-1-醇合成路线 （共 5 条）
反应条件
2: aq. NaOH / ethanol 4: Et3N / dimethylsulfoxide View Scheme
参考文献
Cieslak, Jacek; Ausin, Cristina; Grajkowski, Andrzej; Beaucage, Serge L.
Chemistry - A European Journal, 2013 , vol. 19, # 14 p. 4623 - 4632
反应条件
1: Destillation 2: hydrochloric acid View Scheme
参考文献
Boehm
Monatshefte fuer Chemie, 1906 , vol. 27, p. 955
反应条件
1: Destillation 2: potassium permanganate; water View Scheme
参考文献
Boehm
Monatshefte fuer Chemie, 1906 , vol. 27, p. 955
参考文献
Cieslak, Jacek; Ausin, Cristina; Grajkowski, Andrzej; Beaucage, Serge L.
Chemistry - A European Journal, 2013 , vol. 19, # 14 p. 4623 - 4632
反应条件
1.1: trifluoroacetic anhydride / -15 °C / |Reflux
2.1: methanol / 16 h / 25 °C
3.1: oxalyl dichloride / dimethyl sulfoxide; dichloromethane / 0.42 h / -78 °C
3.2: -78 - 25 °C
4.1: methanol; water; hydrogenchloride / 1 h / 55 °C
5.1: tetrabutyl ammonium fluoride / dimethyl sulfoxide / 0.25 h / 25 °C
View Scheme
参考文献
Cieslak, Jacek; Ausin, Cristina; Grajkowski, Andrzej; Beaucage, Serge L.
Chemistry - A European Journal, 2013 , vol. 19, # 14 p. 4623 - 4632
