2-溴-4,5,6,7-四氢噻唑并[5,4-c]吡啶盐酸盐合成路线 （共 4 条）
反应条件
trifluoroacetic acid in dichloromethane
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 24 p. 7337 - 7343
反应条件
1.1: pyrrolidine; TsOH*H2O / cyclohexane / 2 h / Heating 1.2: 63 percent / S8 / methanol / 5 h / 0 °C 2.1: 49 percent / t-BuONO; CuBr2 / dimethylformamide / 2 h / 50 - 60 °C 3.1: TFA / CH2Cl2 / 0.17 h / 20 °C View Scheme
参考文献
Heterocycles, , vol. 63, # 7 p. 1555 - 1561
反应条件
1: 49 percent / t-BuONO; CuBr2 / dimethylformamide / 2 h / 50 - 60 °C 2: TFA / CH2Cl2 / 0.17 h / 20 °C View Scheme
参考文献
Heterocycles, , vol. 63, # 7 p. 1555 - 1561
反应条件
sodium tris(acetoxy)borohydride; acetic acid; triethylamine in diethyl ether; dichloromethane; water T=20°C; 1 h;
参考文献
Haginoya, Noriyasu; Komoriya, Satoshi; Osanai, Ken; Yoshino, Toshiharu; Nagata, Tsutomu; Nagamochi, Masatoshi; Muto, Ryo; Yamaguchi, Mitsuhiro; Nagahara, Takayasu; Kanno, Hideyuki
Heterocycles, 2004 , vol. 63, # 7 p. 1555 - 1561
