1,2-双(4-氟苯基)乙酮合成路线 （共 22 条）
反应条件
carbon disulfide; aluminium trichloride
反应条件
in diethyl ether T=0 - 5°C; 4 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 8 p. 2843 - 2849
反应条件
1.1: dibutylamine / diethyl ether / 3 h / 20 °C 2.1: toluene-4-sulfonic acid / benzene / 2 h / 50 °C / Inert atmosphere 3.1: sodium hydride / ethanol; benzene / 18 h / 20 °C / Inert atmosphere 3.2: 1 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 20, # 15 p. 4812 - 4819
反应条件
1.1: toluene-4-sulfonic acid / benzene / 2 h / 50 °C / Inert atmosphere 2.1: sodium hydride / ethanol; benzene / 18 h / 20 °C / Inert atmosphere 2.2: 1 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 20, # 15 p. 4812 - 4819
参考文献
Yuki Gosei Kagaku Kyokaishi, , vol. 17, p. 339,340, 777, 779
Chem.Abstr., , p. 17971,1960 4492
参考文献
Yuki Gosei Kagaku Kyokaishi, , vol. 17, p. 339,340, 777, 779
Chem.Abstr., , p. 17971,1960 4492
反应条件
1: chlorobenzene; hydrogenchloride / |liquid HCl View Scheme
反应条件
hydrogenchloride; chloro-trimethyl-silane; sodium hexamethyldisilazane; 3-chloro-benzenecarboperoxoic acid Multistep reaction;
参考文献
Procopiou; Draper; Hutson; Inglis; Ross; Watson
Journal of Medicinal Chemistry, 1993 , vol. 36, # 23 p. 3658 - 3662
反应条件
selenium(IV) oxide in acetic acid Heating;
参考文献
BIOENERGENIX; McCall, John M.; Romero, Donna L.
Patent: US2014/128392 A1, 2014 ;
Location in patent: Paragraph 0235; 0347; 348 ;
反应条件
2: water View Scheme
