(S)-3-羟基-3-苯基丙酸甲酯合成路线 (共 42 条)
反应条件
magnesium T=0 - 20°C; 1 h; Overall yield = 90 percent; Overall yield = 65 mg;
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 46 p. 12143 - 12147
Angew. Chem., , vol. 125, # 46 p. 12365 - 12369,5
反应条件
Title compound not separated from byproducts;
参考文献
Chemische Berichte, , vol. 119, # 7 p. 2191 - 2207
反应条件
1: 1.) CF3COOH; 2.) water / 1.) 0 deg C, 15 min; 2.) 0 deg C, 2 h 2: 1.) 0.1 N NaOH / 1.) water, rt; 2.) ether, 0 deg C, 15 min View Scheme
参考文献
Tetrahedron, , vol. 40, # 19 p. 3769 - 3776
反应条件
sodium hydroxide 1.) water, rt; 2.) ether, 0 deg C, 15 min; Multistep reaction;
参考文献
Tetrahedron, , vol. 40, # 19 p. 3769 - 3776
反应条件
potassium fluoride; tetrafluoroboric acid; 3-chloro-benzenecarboperoxoic acid 2., DMF; Yield given. Multistep reaction;
参考文献
Helvetica Chimica Acta, , vol. 69, p. 1542 - 1545
反应条件
2: 1., HBF4 2., m-chloroperbenzoic acid, KF / 2., DMF View Scheme
参考文献
Helvetica Chimica Acta, , vol. 69, p. 1542 - 1545
参考文献
Journal of the Chemical Society, , vol. 103, p. 117
反应条件
Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 36, # 2 p. 227 - 236
反应条件
multistep reaction, stereoselectivity, other substrates;
参考文献
Journal of the American Chemical Society, , vol. 105, # 23 p. 6968 - 6969
参考文献
Journal of the Chemical Society, Chemical Communications, , p. 162 - 163