4-甲氧基羰酰基苯基硫氰酸酯合成路线 （共 6 条）
反应条件
calcium carbonate in dichloromethane; water 16 h;
参考文献
WO2009/142720 A1, ;
Page/Page column 38-39 ;
反应条件
1: With potassium hydroxide in N,N-dimethyl-formamide T=25 - 28°C; 2: With methyl iodide in N,N-dimethyl-formamide T=10 - 40°C;
参考文献
Russian Journal of Organic Chemistry, , vol. 36, # 8 p. 1173 - 1177
反应条件
1: sodium hydride / tetrahydrofuran; various solvent(s) / 20 h / Heating 2: 89 percent / tosyl chloride; triethylamine / tetrahydrofuran / 1 h / 22 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 72, # 10 p. 3969 - 3971
反应条件
1: p-aminobenzoic acid methyl ester With 1,4-diaza-bicyclo[2.2.2]octane; carbon disulfide T=20°C; 12 h; 2: bis(trichloromethyl) carbonate Reflux;
参考文献
Chemical Biology and Drug Design, , vol. 76, # 1 p. 25 - 33
参考文献
Magnetic Resonance in Chemistry, , vol. 27, # 6 p. 585 - 591
反应条件
1.1: thionyl chloride / 4 h / Reflux 1.2: pH 7 - 8 2.1: 1,4-diaza-bicyclo[2.2.2]octane; carbon disulfide / 12 h / 20 °C 2.2: Reflux View Scheme
参考文献
Chemical Biology and Drug Design, , vol. 76, # 1 p. 25 - 33
