(3-(4-氯苯基)-1-苯基-1H-吡唑-4-基)甲醇合成路线 （共 7 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
1.75 h;
参考文献
De Luca, Lidia; Giacomelli, Giampaolo; Masala, Simonetta; Porcheddu, Andrea
Synlett, 2004 , # 13 p. 2299 - 2302
反应条件
1.1: 25 °C
1.2: dimethylformamide / 16 h / 20 °C
2.1: aq. Na2CO3
3.1: 100 percent / LiAlH4 / tetrahydrofuran / 1.75 h
View Scheme
参考文献
De Luca, Lidia; Giacomelli, Giampaolo; Masala, Simonetta; Porcheddu, Andrea
Synlett, 2004 , # 13 p. 2299 - 2302
反应条件
1.1: 25 °C
1.2: dimethylformamide / 16 h / 20 °C
2.1: aq. Na2CO3
3.1: 100 percent / LiAlH4 / tetrahydrofuran / 1.75 h
View Scheme
参考文献
De Luca, Lidia; Giacomelli, Giampaolo; Masala, Simonetta; Porcheddu, Andrea
Synlett, 2004 , # 13 p. 2299 - 2302
反应条件
1.1: 25 °C
1.2: dimethylformamide / 16 h / 20 °C
2.1: aq. Na2CO3
3.1: 100 percent / LiAlH4 / tetrahydrofuran / 1.75 h
View Scheme
参考文献
De Luca, Lidia; Giacomelli, Giampaolo; Masala, Simonetta; Porcheddu, Andrea
Synlett, 2004 , # 13 p. 2299 - 2302
反应条件
2,2,6,6-tetramethyl-piperidine-N-oxyl; iron(III) chloride in water; ethyl acetate
T=20°C; 4 h;
参考文献
Kumar, R. Senthil; Karthikeyan; Perumal, Paramasivan T.
Canadian Journal of Chemistry, 2008 , vol. 86, # 7 p. 720 - 725
反应条件
1: 100 percent / SOCl2 / benzene / 2.5 h / Heating
2: 98 percent / dimethylsulfoxide / 1 h / 40 - 45 °C
3: 97 percent / 62percent H2SO4 / 2.5 h / 125 °C
View Scheme
参考文献
Rainer; Krueger; Klemm
Arzneimittel-Forschung/Drug Research, 1981 , vol. 31, # 4 p. 649 - 655
反应条件
1: 100 percent / SOCl2 / benzene / 2.5 h / Heating
2: 98 percent / dimethylsulfoxide / 1 h / 40 - 45 °C
View Scheme
参考文献
Rainer; Krueger; Klemm
Arzneimittel-Forschung/Drug Research, 1981 , vol. 31, # 4 p. 649 - 655
