1,4-二溴-2-氟-5-硝基苯合成路线 (共 3 条)
反应条件
hydrogenchloride; tin (II) chloride dihydrate in ethanol T=0°C; Reflux;
参考文献
Zhang, Yong; Chien, Shang-Chieh; Chen, Kung-Shih; Yip, Hin-Lap; Sun, Ying; Davies, Joshua A.; Chen, Fang-Chung; Jen, Alex K.-Y.
Chemical Communications, 2011 , vol. 47, # 39 p. 11026 - 11028
反应条件
tert.-butylnitrite; copper(ll) bromide in acetonitrile
T=60°C;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2007/30366 A1, 2007 ;
Location in patent: Page/Page column 121-122 ;
反应条件
ammonium nitrate; trifluoroacetic acid; trifluoroacetic anhydride in dichloromethane
T=0 - 20°C;
参考文献
Chen; Konstantinov; Chittim; Joyce; Bols; Bunce
Environmental Science and Technology, 2001 , vol. 35, # 18 p. 3749 - 3756