利伐沙班合成路线

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898543-06-14-[4-[(5S)-5-(氨基甲基)-2-氧代-3-恶唑烷基]苯基]-3-吗啉酮盐酸盐+

86427-02-33-氯噻吩-2-甲酰氯

366789-02-8利伐沙班

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42518-98-95-氯-2-酰氯噻吩+

1411775-01-3

366789-02-8利伐沙班

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EGIS GYOGYSZERGYAR NYILVANOSAN MUeKOeDOe RESZVENY-TARSASAG; SIPOS, Eva; KOVANYINE LAX, Gyoergyi; HAVASI, Balazs; VOLK, Balazs; KRASZNAI, Gyoergy; RUZSICS, Gyoergy; BARKOCZY, Jozsef; TOTHNE LAURITZ, Maria; LUKACS, Gyula; BOZA, Andras; HEGEDUeS, Laszlo Jozsef; TABORINE TOTH, Maria Julia; PECSI, Eva
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24065-33-62-氯噻吩-5-甲酸+

1411775-01-3

366789-02-8利伐沙班

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42518-98-95-氯-2-酰氯噻吩+

1446022-16-7

366789-02-8利伐沙班

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WO2013/98833 A2, ;

Page/Page column 40 ;

42518-98-95-氯-2-酰氯噻吩+

1446022-18-9

366789-02-8利伐沙班

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1429333-87-8+

438056-69-04-(4-氨基苯基)吗啉-3-酮

366789-02-8利伐沙班

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SYMED LABS LIMITED; MOHAN RAO, Dodda; KRISHNA REDDY, Pingili; VENKAT REDDY, Buthukuri
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42518-98-95-氯-2-酰氯噻吩+

1416129-92-4

366789-02-8利伐沙班

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SYMED LABS LIMITED; MOHAN RAO, Dodda; KRISHNA REDDY, Pingili; VENKAT REDDY, Buthukuri
Patent: WO2013/46211 A1, 2013 ;
Location in patent: Page/Page column 62; 63 ;

1313613-18-1+

1384257-81-1

366789-02-8利伐沙班

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SYMED LABS LIMITED; MOHAN RAO, Dodda; KRISHNA REDDY, Pingili; VENKAT REDDY, Buthukuri
Patent: WO2013/46211 A1, 2013 ;
Location in patent: Page/Page column 50; 51 ;

1313613-18-1

366789-02-8利伐沙班

参考文献

SYMED LABS LIMITED; MOHAN RAO, Dodda; KRISHNA REDDY, Pingili; VENKAT REDDY, Buthukuri
Patent: WO2013/46211 A1, 2013 ;
Location in patent: Page/Page column 50 ;