3,4-二氨基苯甲酸甲酯合成路线 （共 20 条）
反应条件
thionyl chloride 4 h; Inert atmosphere;
参考文献
Lee, Kyeong; Goo, Ja-Il; Jung, Hwa Young; Kim, Minkyoung; Boovanahalli, Shanthaveerappa K.; Park, Hye Ran; Kim, Mun-Ock; Kim, Dong-Hyun; Lee, Hyun Sun; Choi, Yongseok
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 24 p. 7456 - 7460
反应条件
sodium hydroxide; thionyl chloride; sodium chloride in methanol; dichloromethane
参考文献
Mitsui Chemicals, Inc.
Patent: US5852011 A1, 1998 ;
反应条件
hydrogen; palladium on activated charcoal in methanol
参考文献
Heterocycles, , vol. 32, # 11 p. 2093 - 2097
反应条件
platinum on activated charcoal; ethyl acetate Hydrogenation;
参考文献
Journal of the Chemical Society, , p. 2197,2199
反应条件
1: 70 percent / H2SO4 / 8 h / Heating 2: H2 / 10percent Pd-C/ Raney nickel / methanol / 6 h / 2280 Torr View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 27, # 1-12 p. 1106 - 1109
反应条件
1: 92 percent / H2SO4 / Heating 2: H2 / 5percent Pd/C / methanol View Scheme
参考文献
Heterocycles, , vol. 32, # 11 p. 2093 - 2097
反应条件
1: aqueous hydrochloric acid 2: tin; hydrochloric acid 3: hydrochloric acid View Scheme
反应条件
potassium hydroxide in ethanol; water T=50°C; Inert atmosphere;
参考文献
Perez-Villanueva, Jaime; Hernandez-Campos, Alicia; Yepez-Mulia, Lilian; Mendez-Cuesta, Carlos; Mendez-Lucio, Oscar; Hernandez-Luis, Francisco; Castillo, Rafael
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 14 p. 4221 - 4224
参考文献
Hargrave, Karl D.; Proudfoot, John R.; Grozinger, Karl G.; Cullen, Ernest; Kapadia, Suresh R.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 7 p. 2231 - 2241
反应条件
3 h; Heating / reflux;
参考文献
Pfizer Inc.
Patent: US2004/192698 A1, 2004 ;
Location in patent: Page/Page column 18 ;
