1: 1.) aluminum chloride / 1.) 50 deg C, 1 h, 2.) 80 deg C, 22 h 2: 94 percent / sodium hydroxide, sodium hypochlorite / H2O / 22 h / below 25 deg C 3: thionyl chloride / 4 h / 80 °C View Scheme
参考文献
Chu, Daniel T. W.; Nordeen, Carl W.; Hardy, Dwight J.; Swanson, Robert N.; Giardina, William J.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 168 - 174
1: 1.) aluminum chloride / 1.) 50 deg C, 1 h, 2.) 80 deg C, 22 h 2: 94 percent / sodium hydroxide, sodium hypochlorite / H2O / 22 h / below 25 deg C 3: thionyl chloride / 4 h / 80 °C 4: 1.) biquinoline, n-butyllithium / 1.) THF, -30 deg C to - 5 deg C, 2.) -50 deg C, 0.5 h View Scheme
参考文献
Chu, Daniel T. W.; Nordeen, Carl W.; Hardy, Dwight J.; Swanson, Robert N.; Giardina, William J.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 168 - 174
