反应条件
1: 91 percent / Br2 / acetic acid / 0.25 h / Ambient temperature 2: 1.) 12 N HCl, NaNO2, 2.) 50 percent H3PO2 / 1.) water, 5 deg C, 2.) water, 0 deg C, 3 h 3: 77 percent / N,N-dimethyl-acetamide / 4 h / Heating 4: 71 percent / 90 percent formic acid / Raney nickel alloy / 2 h / Heating View Scheme
参考文献
Kruse, Lawrence I.; Kaiser, Carl; DeWolf, Walter E.; Frazee, James S.; Erickson, Robert W.; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 887 - 889
