2,4-二氟苯胺合成路线

参考文献

Bakshi, Pancham; Jin, Chao; Broutin, Pierre; Berhane, Beniam; Reed, Jon; Mullan, Michael
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 23 p. 8102 - 8112

367-25-92,4-二氟苯胺

59025-55-72,4-二氟苯基异氰酸酯

参考文献

Lebedev; Lebedeva; Sheludyakov; Ovcharuk; Kovaleva; Ustinova
Russian Journal of General Chemistry, 2006 , vol. 76, # 1 p. 110 - 115

367-25-92,4-二氟苯胺

1021854-28-3N-(3-((5-氯-1H-吡咯并[2,3-b]吡啶-3-基)(羟基)甲基)-2,4-二氟苯基)-1-丙磺酰胺

参考文献

Buck, Jason R.; Saleh, Sam; Imam Uddin, Md.; Manning, H. Charles
Tetrahedron Letters, 2012 , vol. 53, # 32 p. 4161 - 4165

367-25-92,4-二氟苯胺

101471-20-92-溴-4,6-二氟苯胺氢溴酸

参考文献

Kruse; Kaiser; DeWolf Jr.; Frazee; Ross; Wawro; Wise; Flaim; Sawyer; Erickson
Journal of Medicinal Chemistry, 1987 , vol. 30, # 3 p. 486 - 494

367-25-92,4-二氟苯胺+

96568-04-62,6-二氯-5-氟烟酰乙酸乙酯+

122-51-0原甲酸三乙酯

100490-99-12-(2,6-二氯-5-氟烟酰基)-3-((2,4-二氟苯基)氨基)丙烯酸乙酯

参考文献

Chu, Daniel T. W.; Fernandes, Prabhavathi B.; Claiborne, Akiyo K.; Gracey, Eugene H.; Pernet, Andre G.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2364 - 2369

367-25-92,4-二氟苯胺+

96568-05-7

100490-99-12-(2,6-二氯-5-氟烟酰基)-3-((2,4-二氟苯基)氨基)丙烯酸乙酯

参考文献

Bouzard, D.; Cesare, P. Di; Essiz, M.; Jacquet, J. P.; Ledoussal, B.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 3 p. 518 - 525

367-25-92,4-二氟苯胺

100491-29-0甲酸乙酯1-(2,4-二氟苯基)-7-氯-6-氟-4-氧代羟基吡啶[2,3-B]吡啶-3-羧酸

参考文献

Bouzard, D.; Cesare, P. Di; Essiz, M.; Jacquet, J. P.; Ledoussal, B.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 3 p. 518 - 525

367-25-92,4-二氟苯胺

136773-69-84-氯-7-氟吡咯并[1,2-a]喹喔啉

参考文献

Campiani; Nacci; Corelli; Anzini
Synthetic Communications, 1991 , vol. 21, # 15-16 p. 1567 - 1576

367-25-92,4-二氟苯胺

33264-82-32-氨基-5-氟苯硫酚

参考文献

Van Zandt, Michael C.; Jones, Michael L.; Gunn, David E.; Geraci, Leo S.; Jones, J. Howard; Sawicki, Diane R.; Sredy, Janet; Jacot, Jorge L.; DiCioccio, A. Thomas; Petrova, Tatiana; Mitschler, Andre; Podjarny, Alberto D.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 9 p. 3141 - 3152

35727-88-92,4-二氯-6-[(2,4-二氟苯基)氨基]苯-1,3,5-三甲腈

参考文献

Heilman; Battershell; Pyne; Goble; Magee
Journal of Medicinal Chemistry, 1978 , vol. 21, # 9 p. 906 - 913