5-甲基-2-吡啶-2-基-1,2-二氢-吡唑-3-酮合成路线 （共 4 条）
反应条件
acetic acid
1 h; Heating / reflux;
参考文献
XENON PHARMACEUTICALS INC.
Patent: WO2008/121861 A2, 2008 ;
Location in patent: Page/Page column 62 ;
WO 2008/121861 A2
反应条件
in acetonitrile
Heating;
参考文献
Pegurier, Cecile; Collart, Philippe; Danhaive, Pierre; Defays, Sabine; Gillard, Michel; Gilson, Frederic; Kogej, Thierry; Pasau, Patrick; Van Houtvin, Nathalie; Van Thuyne, Marc; van Keulen, BerendJan
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 15 p. 4228 - 4231
反应条件
1: hydrazine hydrate
2: Destillation des entstehenden Hydrazons unter vermindertem Druck
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参考文献
Fargher; Furness
Journal of the Chemical Society, 1915 , vol. 107, p. 695
反应条件
1: PCl5; POCl3 / 160 °C
2: hydrazine hydrate
3: Destillation des entstehenden Hydrazons unter vermindertem Druck
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参考文献
Fargher; Furness
Journal of the Chemical Society, 1915 , vol. 107, p. 695
