2-[3-(三氟甲基)苯氧基]烟酸合成路线 （共 5 条）
反应条件
copper(l) iodide; copper; potassium carbonate in N,N-dimethyl-formamide T=140°C; 0.5 h; Microwave irradiation;
参考文献
Bissantz, Caterina; Dehmlow, Henrietta; Martin, Rainer E.; Obst Sander, Ulrike; Richter, Hans; Ullmer, Christoph
Patent: US2010/105906 A1, 2010 ;
Location in patent: Page/Page column 22 ;
US 20100105906 A1
反应条件
sodium methylate in methanol
参考文献
Stauffer Chemical Company
Patent: US4251263 A1, 1981 ;
反应条件
in N,N-dimethyl-formamide
参考文献
Molecular Pharmacology, , vol. 69, # 1 p. 165 - 173
反应条件
potassium hydroxide in water 60 h; Heating;
参考文献
Rouchaud, Jean; Gustin, Fabrice; Moulart, Claude; Herin, Marc
Bulletin des Societes Chimiques Belges, 1990 , vol. 99, # 5 p. 339 - 344
反应条件
thionyl chloride; triethylamine in dichloromethane; water; toluene
参考文献
May and Baker Limited
Patent: US4618366 A1, 1986 ;
