2-苯基咪唑并[1,2-a]吡啶-3-甲醛合成路线 （共 16 条）
反应条件
1: 64 percent / ethanol / 96 h / Heating 2: 95 percent / 0.5N NaOH / 2 h / Ambient temperature View Scheme
参考文献
Chemische Berichte, , vol. 118, # 9 p. 4099 - 4130
反应条件
1: 88 percent / benzene / Ambient temperature; room temp., 8-10 days or reflux, 30-40 h 2: 91 percent / aq.NaOH View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 16, # 4 p. 409 - 417
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 16, # 4 p. 528 - 537
反应条件
1: tetrahydrofuran / -78 - 20 °C / Molecular sieve; Inert atmosphere 2: [copperl(II)(1,1,1,5,5,5-hexafluoroacetylacetonate)2] monohydrate; oxygen / N,N-dimethyl-formamide / 6.5 h / 105 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 25 p. 5678 - 5681
反应条件
1: toluene-4-sulfonic acid / tetrahydrofuran / 18 h / Molecular sieve; Inert atmosphere; Reflux 2: tetrahydrofuran / -78 - 20 °C / Molecular sieve; Inert atmosphere 3: [copperl(II)(1,1,1,5,5,5-hexafluoroacetylacetonate)2] monohydrate; oxygen / N,N-dimethyl-formamide / 6.5 h / 105 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 25 p. 5678 - 5681
反应条件
azido-acetic acid ethyl ester; sodium ethanolate 1.) -30 deg C, 2 h, 2.) -30 deg C to room temp., 3 h;
参考文献
Journal of Organic Chemistry, , vol. 59, # 21 p. 6413 - 6418
反应条件
sodium ethanolate in ethanol 1.) -30 deg C, 2 h, 2.) -30 deg C to room temp., 3 h;
参考文献
Journal of Organic Chemistry, , vol. 59, # 21 p. 6413 - 6418
