5-(4-甲氧基苯基)异噁唑合成路线 （共 12 条）
反应条件
hydrogenchloride in dichloromethane; water T=20°C; 1 h;
参考文献
Kivrak, Arif; Zora, Metin
Tetrahedron, 2014 , vol. 70, # 4 p. 817 - 831
反应条件
hydroxylamine-o-sulphonic acid in methanol 0.333333 h; Ambient temperature;
参考文献
Lin, Yang-i; Lang, Stanley, A.
Journal of Organic Chemistry, 1980 , vol. 45, # 24 p. 4857 - 4860
反应条件
hydrogenchloride; hydroxylamine hydrochloride in ethanol; water T=80°C; 16 h; Inert atmosphere;
参考文献
Gogsig, Thomas M.; Nielsen, Dennis U.; Lindhardt, Anders T.; Skrydstrup, Troels
Organic Letters, 2012 , vol. 14, # 10 p. 2536 - 2539
反应条件
1: NaH / tetrahydrofuran / 2.5 h / 20 °C 2: NH2OH*HCl / tetrahydrofuran; H2O / 17 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 23 p. 6058 - 6062
反应条件
hydroxylamine hydrochloride in tetrahydrofuran; water T=20°C; 17 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 23 p. 6058 - 6062
反应条件
pyridine; hydroxylamine hydrochloride in ethanol T=78°C; 16 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 45, # 3 p. 879 - 885
反应条件
1: [Pd(η3-1-Ph-allyl)(μ-Cl)]2; N,N-dicyclohexylmethylamine; N-ethyl-N,N-diisopropylamine; bis(dibenzylideneacetone)-palladium(0); [(t-Bu)3PH]BF4 / 1,4-dioxane / 17 h / 100 °C / Inert atmosphere 2: hydrogenchloride; hydroxylamine hydrochloride / ethanol; water / 16 h / 80 °C / Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 14, # 10 p. 2536 - 2539
反应条件
hydroxylamine hydrochloride T=20°C; 17 h;
参考文献
Nakamura, Toshio; Sato, Masakazu; Kakinuma, Hiroyuki; Miyata, Noriyuki; Taniguchi, Kazuo; Bando, Kagumi; Koda, Ayumi; Kameo, Kazuya
Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5416 - 5427
反应条件
1: NH2OH*HCl, CH3ONa / methanol / 5 h / Heating 2: hydrochloric acid / methanol / 1 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, p. 461 - 464
反应条件
1: 86 percent / dimethylformamide / 8 h / Heating 2: NH2OH*HCl, CH3ONa / methanol / 5 h / Heating 3: hydrochloric acid / methanol / 1 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, p. 461 - 464
