6-(4-溴苯基)-4,5-二氢-2H-哒嗪-3-酮合成路线 （共 6 条）
反应条件
hydrazine in ethanol 2 h; Heating / reflux;
参考文献
ABBOTT LABORATORIES
Patent: WO2006/65233 A1, 2006 ;
Location in patent: Page/Page column 75 ;
参考文献
Abbott Laboratories
Patent: US2005/245531 A1, 2005 ;
US 20050245531 A1
反应条件
1: AlCl3, aluminium chloride / Reflux 2: sodium acetate; hydrazine hydrate / methanol / 6 h / Reflux View Scheme
参考文献
Acta Poloniae Pharmaceutica - Drug Research, , vol. 67, # 5 p. 555 - 562
反应条件
in water; trichlorophosphate
参考文献
Abbott Laboratories
Patent: US2005/245531 A1, 2005 ;
US 20050245531 A1
反应条件
bromine in acetic acid
T=20 - 100°C; 1 h;
参考文献
ABBOTT LABORATORIES
Patent: WO2006/65233 A1, 2006 ;
Location in patent: Page/Page column 75-76 ;
反应条件
1: trichlorophosphate / 6 h / Heating
2: hydrazine hydrate / ethanol / 16 h / Reflux
View Scheme
参考文献
Islam, Mojahidul; Siddiqui, Anees A.
Acta Poloniae Pharmaceutica - Drug Research, 2010 , vol. 67, # 5 p. 555 - 562
