1.1: aq. KOH; n-Bu4NBr / methanol / 8 h / 20 °C 1.2: aq. HCl / CH2Cl2 / 5 - 10 °C 2.1: 10.4 g / H2 / Pd(OH)2/C / ethyl acetate / 15 h / 20 °C / 7600 Torr 3.1: aq. HBr / 42 h / Heating 4.1: aq. KOH; n-Bu4NBr / 0.25 h / 20 °C 4.2: 20.1 g / aq. KOH / toluene / 6.5 h / 20 °C / pH 9 - 10 View Scheme