甲基2,3-二溴-2-甲基丙酸酯合成路线 （共 15 条）
反应条件
1: T=68°C; 14 h; Inert atmosphere; 2: With sodium hydrogen sulphate monohydrate T=160°C; P=760.051 Torr; Inert atmosphere;
参考文献
Kuttruff, Christian A.; Geiger, Simon; Cakmak, Mesut; Mayer, Peter; Trauner, Dirk
Organic Letters, 2012 , vol. 14, # 4 p. 1070 - 1073
反应条件
in methanol T=25°C; 16 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Walkup, Robert D.; Obeyesekere, Nihal U.
Synthesis, 1987 , # 7 p. 607 - 611
参考文献
Yang, Ke-Wu; Golich, Frank C.; Sigdel, Tara K.; Crowder, Michael W.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 23 p. 5150 - 5153
反应条件
bromine in water
T=30°C; other temperatures (22, 38, 46, 54 deg C), ΔH*, ΔS*, ΔG*; Rate constantThermodynamic dataProduct distribution;
参考文献
Mohamed Farook, Syed Ahamed; Viswanathan, Seshaiyer; Ganesan, Ramachandran
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 5 p. 1394 - 1400
反应条件
in methanol
Dehydrobromination; addition; 1 h; Heating;
参考文献
Gambacorta, Augusto; Farah, Mohamed Elmi; Tofani, Daniela
Tetrahedron, 1999 , vol. 55, # 43 p. 12615 - 12628
反应条件
in methanol
T=25°C; 16 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Walkup, Robert D.; Obeyesekere, Nihal U.
Synthesis, 1987 , # 7 p. 607 - 611
反应条件
1: NaOMe / methanol
View Scheme
参考文献
Texier,F.; Bourgois,J.
Bulletin de la Societe Chimique de France, 1976 , p. 487 - 492
反应条件
1: NaOMe / methanol
View Scheme
参考文献
Texier,F.; Bourgois,J.
Bulletin de la Societe Chimique de France, 1976 , p. 487 - 492
参考文献
Texier,F.; Bourgois,J.
Bulletin de la Societe Chimique de France, 1976 , p. 487 - 492
反应条件
1: methanol / Erhitzen des Reaktionsprodukts mit wenig Kaliumhydrogensulfat,Natriummethylat oder Natriumhydrogensulfat bis auf 170grad
2: H2SO4
View Scheme
参考文献
Bieber
Annales de Chimie (Cachan, France), 1954 , vol. <12>9, p. 674,676
