BOC-L-苯丙氨酸琥珀酰亚胺酯合成路线 （共 19 条）
反应条件
1: NaBH4; AcOH / methanol; dioxane 2: MnO2 / CHCl3 / 18 h / 20 °C View Scheme
参考文献
Synlett, , # 18 art. no. G24405ST, p. 2802 - 2804
反应条件
sodium hydrogencarbonate in ethanol; water; acetone T=20°C; 5 h;
参考文献
Popovic, Stanimir; Bieraeugel, Hans; Detz, Remko J.; Kluwer, Alexander M.; Koole, Jelmer A. A.; Streefkerk, Dieuwertje E.; Hiemstra, Henk; Van Maarseveen, Jan H.
Chemistry - A European Journal, 2013 , vol. 19, # 50 p. 16934 - 16937
反应条件
1: 82 percent / Et3N / CH2Cl2 / 20 °C 2: aq. LiOH / methanol / 5 h View Scheme
参考文献
Ding, Bangwei; Taotofa, Uale; Orsak, Thomas; Chadwell, Matthew; Savage, Paul B.
Organic Letters, 2004 , vol. 6, # 20 p. 3433 - 3436
反应条件
1: tetrahydrofuran / 20 °C 2: CH2Cl2 / 2 h / 0 °C View Scheme
参考文献
Wallen, Erik A. A.; Christiaans, Johannes A. M.; Jarho, Elina M.; Forsberg, Markus M.; Venaelaeinen, Jarkko I.; Maennistoe, Pekka T.; Gynther, Jukka
Journal of Medicinal Chemistry, 2003 , vol. 46, # 21 p. 4543 - 4551
反应条件
in dichloromethane T=0°C; 1 h;
参考文献
Obrecht; Bohdal; Broger; Bur; Lehmann; Ruffieux; Schonholzer; Spiegler; Muller
Helvetica Chimica Acta, 1995 , vol. 78, # 3 p. 563 - 580
反应条件
1: 95 percent / dimethylformamide / Ambient temperature 2: CF3COOH / methanol / 1 h / Ambient temperature View Scheme
参考文献
Kulikov, S. V.; Sokolova, N. Yu.; Rodin, S. V.; Samartsev, M. A.
Chemistry of Natural Compounds, 1983 , vol. 19, # 4 p. 469 - 475
Khimiya Prirodnykh Soedinenii, 1983 , vol. 19, # 4 p. 499 - 504
反应条件
sodium hydrogencarbonate in ethanol; water; acetone
T=20°C; 5 h;
参考文献
Popovic, Stanimir; Bieraeugel, Hans; Detz, Remko J.; Kluwer, Alexander M.; Koole, Jelmer A. A.; Streefkerk, Dieuwertje E.; Hiemstra, Henk; Van Maarseveen, Jan H.
Chemistry - A European Journal, 2013 , vol. 19, # 50 p. 16934 - 16937
反应条件
(i) <PhCH2NMe3>OH, (ii) /BRN= 715573/; Multistep reaction;
参考文献
Wang,S.-S. et al.
Journal of Organic Chemistry, 1977 , vol. 42, p. 1286 - 1290
反应条件
1: N-methylmorpholine / dimethylformamide / 8 h / Ambient temperature
2: aq. 90 percent TFA, anisole
View Scheme
参考文献
Marastoni; Salvadori; Balboni; Scaranari; Borea; Tomatis
Arzneimittel-Forschung/Drug Research, 1995 , vol. 45, # 2 p. 116 - 119
