2-甲基-2-苯基-1,3-二氧戊环合成路线 （共 91 条）
反应条件
pyridinium p-toluenesulfonate in water T=100°C; 5 h; Product distribution;
参考文献
McClelland, Robert A.; Watada, Brian; Lew, Calvin S. Q.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1993 , # 10 p. 1723 - 1728
反应条件
N,N,N',N,-tetramethylethylenediamine in hexane T=20°C; 18 h; Yield given;
参考文献
Ho, Tse-Lok
Synthetic Communications, 1983 , vol. 13, # 9 p. 769 - 772
反应条件
multistep reaction, products isolated in the course of reaction; Product distribution;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 21, # 11 p. 1297 - 1298
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 21, # 11 p. 1571 - 1572
反应条件
cation exchange resin KU-2 in H+ form T=150°C; 6 h;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 21, # 11 p. 1297 - 1298
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 21, # 11 p. 1571 - 1572
反应条件
multistep reaction, products isolated in the course of reaction; Product distribution;
参考文献
Musavirov, R. S.; Mullakhmetova, Z. F.; Nedogrei, E. P.; Kantor, E. A.; Rakmankulov, D. L.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1985 , vol. 21, # 11 p. 1297 - 1298
Khimiya Geterotsiklicheskikh Soedinenii, 1985 , vol. 21, # 11 p. 1571 - 1572
反应条件
methyl iodide in toluene T=80 - 90°C; 12 h; Title compound not separated from byproducts.;
参考文献
Iwata, Arihiro; Tang, Heqing; Kunai, Atsutaka; Ohshita, Joji; Yamamoto, Yasushi; Matui, Chinami
Journal of Organic Chemistry, 2002 , vol. 67, # 15 p. 5170 - 5175
反应条件
1: 2-phenyl-2-methyl-1,3-dioxolane With water; sodium lauryl sulfate; toluene-4-sulfonic acid in hexanes T=25°C; 5 h; polydimethylsiloxane (PDMS) thimble; 2: phenyl-magnesium bromide in hexanes; diethyl ether T=25°C; 16 h; 3: With water in hexanes; diethyl ether
参考文献
University of Iowa Research Foundation
Patent: US2009/299102 A1, 2009 ;
Location in patent: Page/Page column 5; 7 ;
反应条件
1: 2-phenyl-2-methyl-1,3-dioxolane With sodium lauryl sulfate; toluene-4-sulfonic acid in hexane; water T=25°C; 5 h; 2: Bromure de phenyl magnesium in diethyl ether; hexane T=25°C; 16 h; Further stages.;
参考文献
Runge, M. Brett; Mwangi, Martin T.; Miller II, A. Lee; Perring, Mathew; Bowden, Ned B.
Angewandte Chemie - International Edition, 2008 , vol. 47, # 5 p. 935 - 939
反应条件
diethyl ether; lithium perchlorate T=28°C; 16 h;
参考文献
Saraswathy, V. Geetha; Sankararaman, S.
Journal of Organic Chemistry, 1994 , vol. 59, # 16 p. 4665 - 4670
反应条件
naphthalene; lithium 1.) THF, -40 deg C, 45 min, 2.) THF, -40 deg C, 1 h, 3.) THF, -40 to 20 deg C, overnight; Yield given. Multistep reaction;
参考文献
Gil, Juan F.; Ramon, Diego J.; Yus, Miguel
Tetrahedron, 1993 , vol. 49, # 42 p. 9535 - 9546
