2-溴-3’,5’-二乙酰氧基苯乙酮合成路线 （共 4 条）
反应条件
bromine in carbon disulfide
参考文献
Otsuka Pharmaceutical Co., Ltd.
Patent: US5643932 A1, 1997 ;
反应条件
bromine; acetic acid T=20°C; 1 h;
参考文献
Taketomi, Shohei; Asano, Masayoshi; Higashi, Toshinori; Shoji, Mitsuru; Sugai, Takeshi
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 84, p. 83 - 88
反应条件
hydrogen bromide; acetic acid und Erwaermen des Reaktionsprodukts mit Acetanhydrid und wenig H2SO4;
参考文献
Kloetzel; Abadir
Journal of the American Chemical Society, 1955 , vol. 77, p. 3823,3826
反应条件
1: sodium chloride / acetonitrile; water / 2.5 h / |Reflux
2: Candida antarctica lipase B; water / toluene; aq. phosphate buffer / 15.5 h / 50 °C / pH 7 / |Inert atmosphere; |Enzymatic reaction
View Scheme
参考文献
Taketomi, Shohei; Asano, Masayoshi; Higashi, Toshinori; Shoji, Mitsuru; Sugai, Takeshi
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 84, p. 83 - 88
