反应条件
1: methyl vinyl sulphone With bromine in dichloromethane
6 h; Reflux;
2: 2-hydroxynaphthalene-1,4-dione With 1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran; dichloromethane
6.83333 h; Cooling with iceReflux;
参考文献
Zhoushan HaiZhongZhou Xinsheng Pharmaceuticals Co., Ltd.; Jiang, Zhiwei; Wang, Aijin; Li, Xian; Li, Qingrong; Hu, Hongwei; Xu, Jiali; Hu, Yuesong; Ye, Yan
Patent: US2013/150437 A1, 2013 ;
Location in patent: Paragraph 0153 ;