4-氯吡咯并嘧啶合成路线

参考文献

LaMontagne, Maurice P.; Smith, David C.; Wu, Geng-Shuen
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 295 - 299

参考文献

Liu, Yang; Fang, Jianping; Cai, Haiyan; Xiao, Fei; Ding, Kan; Hu, Youhong
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 18 p. 5473 - 5482

75-30-92-碘代丙烷+

3680-69-14-氯吡咯并嘧啶

870706-47-1

参考文献

Arcari, Joel T.; Beebe, Jean S.; Berliner, Martin A.; Bernardo, Vincent; Boehm, Merin; Borzillo, Gary V.; Clark, Tracey; Cohen, Bruce D.; Connell, Richard D.; Frost, Heather N.; Gordon, Deborah A.; Hungerford, William M.; Kakar, Shefali M.; Kanter, Aaron; Keene, Nandell F.; Knauth, Elizabeth A.; Lagreca, Susan D.; Lu, Yong; Martinez-Alsina, Louis; Marx, Matthew A.; Morris, Joel; Patel, Nandini C.; Savage, Doug; Soderstrom, Cathy I.; Thompson, Carl; Tkalcevic, George; Tom, Norma J.; Vajdos, Felix F.; Valentine, James J.; Vincent, Patrick W.; Wessel, Matthew D.; Chen, Jinshan M.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 10 p. 3059 - 3063

3680-69-14-氯吡咯并嘧啶

870706-48-2

参考文献

Arcari, Joel T.; Beebe, Jean S.; Berliner, Martin A.; Bernardo, Vincent; Boehm, Merin; Borzillo, Gary V.; Clark, Tracey; Cohen, Bruce D.; Connell, Richard D.; Frost, Heather N.; Gordon, Deborah A.; Hungerford, William M.; Kakar, Shefali M.; Kanter, Aaron; Keene, Nandell F.; Knauth, Elizabeth A.; Lagreca, Susan D.; Lu, Yong; Martinez-Alsina, Louis; Marx, Matthew A.; Morris, Joel; Patel, Nandini C.; Savage, Doug; Soderstrom, Cathy I.; Thompson, Carl; Tkalcevic, George; Tom, Norma J.; Vajdos, Felix F.; Valentine, James J.; Vincent, Patrick W.; Wessel, Matthew D.; Chen, Jinshan M.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 10 p. 3059 - 3063

3680-69-14-氯吡咯并嘧啶

876343-09-8

参考文献

Kaspersen, Svein Jacob; Han, Jin; Norsett, Kristin G.; Rydsa, Line; Kjobli, Eli; Bugge, Steffen; Bjorkoy, Geir; Sundby, Eirik; Hoff, Bard Helge
European Journal of Pharmaceutical Sciences, 2014 , vol. 59, # 1 p. 69 - 82

3680-69-14-氯吡咯并嘧啶

908287-23-0

参考文献

INFINITY PHARMACEUTICALS INC.; INTELLIKINE, LLC; CASTRO, Alfredo, C.; EVANS, Catherine, A.; JANARDANANNAIR, Somarajannair; LESCARBEAU, Andre; LIU, Tao; SNYDER, Daniel, A.; TREMBLAY, Martin, R.; REN, Pingda; LIU, Yi; LI, Liansheng; CHAN, Katrina
Patent: WO2013/12915 A1, 2013 ;
WO 2013/012915 A1

75-16-1甲基溴化镁+

3680-69-14-氯吡咯并嘧啶

945950-37-84-甲基-7H-吡咯并[2,3-d]嘧啶

参考文献

PLEXXIKON, INC.; IBRAHIM, Prabha, N.; SPEVAK, Wayne; CHO, Hanna; SHI, Songyuan; ZHANG, Chao; ZHANG, Ying
Patent: WO2011/63159 A1, 2011 ;
Location in patent: Page/Page column 182 ;

75-24-1三甲基铝+

3680-69-14-氯吡咯并嘧啶

945950-37-84-甲基-7H-吡咯并[2,3-d]嘧啶

参考文献

Thiyagarajan, Anandarajan; Salim, Mohammed T.A.; Balaraju, Tuniki; Bal, Chandralata; Baba, Masanori; Sharon, Ashoke
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 24 p. 7742 - 7747

67-56-1甲醇+

3680-69-14-氯吡咯并嘧啶

4786-76-94-甲氧基-7h-吡咯并[2,3-d]嘧啶

参考文献

PLEXXIKON, INC.; IBRAHIM, Prabha, N.; SPEVAK, Wayne; CHO, Hanna; SHI, Songyuan; ZHANG, Chao; ZHANG, Ying
Patent: WO2011/63159 A1, 2011 ;
Location in patent: Page/Page column 181 ;

3680-69-14-氯吡咯并嘧啶+

100-46-9苄胺

60972-04-5N-苄基-7H-吡咯并[2,3-d]嘧啶-4-胺

参考文献

Tedder, Martina E.; Nie, Zhe; Margosiak, Stephen; Chu, Shaosong; Feher, Victoria A.; Almassy, Robert; Appelt, Krzysztof; Yager, Kraig M.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 12 p. 3165 - 3168