5-(羟基甲基)-2-糠酸甲酯合成路线 （共 23 条）
反应条件
1: in methanol; hexanes; benzene T=20°C; 2.25 h; 2: With sodium tetrahydroborate in methanol T=0 - 20°C; 3 h;
参考文献
Washington, University of
Patent: US2008/103192 A1, 2008 ;
Location in patent: Page/Page column 12 ;
反应条件
sodium methylate in methanol T=20°C; 24 h;
参考文献
Schmuck, Carsten; Machon, Uwe
European Journal of Organic Chemistry, 2006 , # 19 p. 4385 - 4392
反应条件
sodium tetrahydroborate in methanol 2 h;
参考文献
Braisted, Andrew C.; Oslob, Johan D.; Delano, Warren L.; Hyde, Jennifer; McDowell, Robert S.; Waal, Nathan; Yu, Chul; Arkin, Michelle R.; Raimundo, Brian C.
Journal of the American Chemical Society, 2003 , vol. 125, # 13 p. 3714 - 3715
反应条件
C20H25N2(1+)*Cl(1-); oxygen; 1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile T=20°C; 16 h; Schlenk technique; chemoselective reaction;
参考文献
Moehlmann, Lennart; Ludwig, Stefan; Blechert, Siegfried
Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 602 - 607
反应条件
1: benzene; methanol; hexane / 1 h / 20 °C 2: sodium borohydride / methanol / 2 h View Scheme
参考文献
Braisted, Andrew C.; Oslob, Johan D.; Delano, Warren L.; Hyde, Jennifer; McDowell, Robert S.; Waal, Nathan; Yu, Chul; Arkin, Michelle R.; Raimundo, Brian C.
Journal of the American Chemical Society, 2003 , vol. 125, # 13 p. 3714 - 3715
反应条件
1: 67 percent / zinc chloride; HCl / CH2Cl2 / 2.5 h / 35 °C 2: 93 percent / NaOAc / acetic acid / 5.5 h / 120 °C 3: 89 percent / NaOMe / methanol / 24 h / 20 °C View Scheme
参考文献
Moldenhauer et al.
Justus Liebigs Annalen der Chemie, 1953 , vol. 580, p. 169,187
参考文献
Nielek, S.; Leslak, T.
Journal fuer Praktische Chemie (Leipzig), 1988 , vol. 330, # 5 p. 825 - 829
反应条件
oxygen T=130°C; P=7500.75 Torr; 2 h; Autoclave;
参考文献
Casanova; Iborra; Corma
Journal of Catalysis, 2009 , vol. 265, # 1 p. 109 - 116
反应条件
oxygen T=130°C; P=7500.75 Torr; 24 h; Autoclave;
参考文献
Casanova; Iborra; Corma
Journal of Catalysis, 2009 , vol. 265, # 1 p. 109 - 116
反应条件
sulfuric acid 3 h; Heating;
参考文献
Nielek, S.; Leslak, T.
Journal fuer Praktische Chemie (Leipzig), 1988 , vol. 330, # 5 p. 825 - 829
