4-亚甲基四氢-2H-吡喃合成路线 （共 26 条）
反应条件
1: 50 percent / lithium diisopropyl amide; potassium tert-butoxide / tetrahydrofuran / 2 h / -50 °C
2: 92 percent / 4-(N,N-dimethylamino)pyridine / CH2Cl2 / 2 h
View Scheme
参考文献
Wu, Zheng; Wouters, Johan; Poulter, C. Dale
Journal of the American Chemical Society, 2005 , vol. 127, # 49 p. 17433 - 17438
反应条件
1: 50 percent / lithium diisopropyl amide; potassium tert-butoxide / tetrahydrofuran / 2 h / -50 °C
2: 92 percent / 4-(N,N-dimethylamino)pyridine / CH2Cl2 / 2 h
3: 43 percent / tris(tetra-n-butylammonium) hydrogen pyrophosphate / acetonitrile / 20 °C
View Scheme
参考文献
Wu, Zheng; Wouters, Johan; Poulter, C. Dale
Journal of the American Chemical Society, 2005 , vol. 127, # 49 p. 17433 - 17438
反应条件
bromine in tetrachloromethane
参考文献
Murza, M.M.; Safarov, M.G.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1994 , vol. 30, # 7 p. 771 - 772
Khimiya Geterotsiklicheskikh Soedinenii, 1994 , # 7 p. 896 - 897
反应条件
aluminum oxide; sodium in n-heptane
T=60°C; 2 h; other time, temperature; Product distribution;
参考文献
Ibatullin, U. G.; Petrushina, T. F.; Akhmadeeva, A. A.; Safarov, M. G.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1985 , vol. 21, # 3 p. 262 - 264
Khimiya Geterotsiklicheskikh Soedinenii, 1985 , vol. 21, # 3 p. 318 - 320
反应条件
sodium hydroxide; pentacarbonyliron(0)
T=180°C; 10 h; autoclave, other time; Product distribution;
参考文献
Ibatullin, U. G.; Petrushina, T. F.; Akhmadeeva, A. A.; Safarov, M. G.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1985 , vol. 21, # 3 p. 262 - 264
Khimiya Geterotsiklicheskikh Soedinenii, 1985 , vol. 21, # 3 p. 318 - 320
反应条件
hydrogenchloride; triethylsilane; aluminium trichloride in dichloromethane
3 h; Ambient temperatureother reaction times.; Product distributionMechanism;
参考文献
Kursanov, D. N.; Bolestova, G. I.; Ibatullin, U. G.; Kuramshina, E. A.; Parnes, Z. N.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, # 11 p. 2078 - 2085
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 11 p. 2274 - 2282
