3-氨基-1,2-苯并异恶唑-6-甲胺合成路线 （共 5 条）
反应条件
borane-THF
T=20°C; 15 h;
参考文献
Cui, Jingrong Jean; Araldi, Gian-Luca; Reiner, John E.; Reddy, Komandla Malla; Kemp, Scott J.; Ho, Jonathan Z.; Siev, Daniel V.; Mamedova, Lala; Gibson, Tony S.; Gaudette, John A.; Minami, Nathaniel K.; Anderson, Susanne M.; Bradbury, Annette E.; Nolan, Thomas G.; Semple
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 20 p. 2925 - 2930
反应条件
hydrogenchloride in ethanol
Heating;
参考文献
Trujillo, John I.; Huang, Horng-Chih; Neumann, William L.; Mahoney, Matthew W.; Long, Scott; Huang, Wei; Garland, Danny J.; Kusturin, Carrie; Abbas, Zaheer; South, Michael S.; Reitz, David B.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 16 p. 4568 - 4574
反应条件
1: Me2CNOH; t-BuOK / tetrahydrofuran
2: aq. HCl / ethanol / Heating
View Scheme
参考文献
Trujillo, John I.; Huang, Horng-Chih; Neumann, William L.; Mahoney, Matthew W.; Long, Scott; Huang, Wei; Garland, Danny J.; Kusturin, Carrie; Abbas, Zaheer; South, Michael S.; Reitz, David B.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 16 p. 4568 - 4574
反应条件
1: dimethylformamide / Heating
2: CH3CONHOH; KO-t-Bu / dimethylformamide / 39 h / 20 - 70 °C
3: BH3*THF / 15 h / 20 °C
View Scheme
参考文献
Cui, Jingrong Jean; Araldi, Gian-Luca; Reiner, John E.; Reddy, Komandla Malla; Kemp, Scott J.; Ho, Jonathan Z.; Siev, Daniel V.; Mamedova, Lala; Gibson, Tony S.; Gaudette, John A.; Minami, Nathaniel K.; Anderson, Susanne M.; Bradbury, Annette E.; Nolan, Thomas G.; Semple
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 20 p. 2925 - 2930
反应条件
1: CH3CONHOH; KO-t-Bu / dimethylformamide / 39 h / 20 - 70 °C
2: BH3*THF / 15 h / 20 °C
View Scheme
参考文献
Cui, Jingrong Jean; Araldi, Gian-Luca; Reiner, John E.; Reddy, Komandla Malla; Kemp, Scott J.; Ho, Jonathan Z.; Siev, Daniel V.; Mamedova, Lala; Gibson, Tony S.; Gaudette, John A.; Minami, Nathaniel K.; Anderson, Susanne M.; Bradbury, Annette E.; Nolan, Thomas G.; Semple
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 20 p. 2925 - 2930
