反-4-羟基环己烷羧酸合成路线

99-96-7对羟基苯甲酸

3685-22-1顺-4-羟基环己甲酸

参考文献

Hirsch, Jerry A.; Truc, Vu Chi
Journal of Organic Chemistry, 1986 , vol. 51, # 12 p. 2218 - 2227

3685-22-1顺-4-羟基环己甲酸

参考文献

RCA Corporation
Patent: US4013582 A1, 1977 ;

3618-04-0反-4-羟基环己烷甲酸乙酯

3685-22-1顺-4-羟基环己甲酸

参考文献

Lang, Lixin; Jagoda, Elaine; Schmall, Bernard; Vuong, Bik-Kee; Adams, H. Richard; Nelson, David L.; Carson, Richard E.; Eckelman, William C.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 9 p. 1576 - 1586

874-61-34-羰基环己羧酸

3685-22-1顺-4-羟基环己甲酸

参考文献

Perkin
Journal of the Chemical Society, 1904 , vol. 85, p. 422

6940-58-51,3,5-戊三羧酸

3685-22-1顺-4-羟基环己甲酸

参考文献

Perkin
Journal of the Chemical Society, 1904 , vol. 85, p. 422

7732-18-5水+

99-96-7对羟基苯甲酸

3685-22-1顺-4-羟基环己甲酸

参考文献

Balas; Kosik
Chem. Zentralbl., 1928 , vol. 99, # I p. 1173

3685-26-5反-4-羟基环己烷羧酸+

74-88-4甲基碘

3618-03-9

参考文献

Mogi, Muneto; Yamada, Ken; Yasoshima, Kayo; Kawanami, Toshio; Umemura, Ichiro; Iwaki, Yuki; Qin, Hongbo; Imase, Hidetomo
Patent: US2009/118287 A1, 2009 ;
Location in patent: Page/Page column 71 ;

3618-03-9

参考文献

MERCK SHARP and DOHME CORP.; ALI, Amjad; NARGUND, Ravi; LO, Michael Man-Chu; YAN, Lin; HUO, Pei; FRANKLIN, Christopher
Patent: WO2011/53519 A1, 2011 ;
Location in patent: Page/Page column 17-18 ;

3685-26-5反-4-羟基环己烷羧酸+

18107-18-1三甲基硅烷化重氮甲烷

3618-03-9

参考文献

SANOFI; Fett, Eykmar; Mougenot, Patrick; Namane, Claudie; Nicolai, Eric; Philippo, Christophe
Patent: US2012/40984 A1, 2012 ;
Location in patent: Paragraph 0350 ;

186581-53-3重氮甲烷+

3685-26-5反-4-羟基环己烷羧酸

3618-03-9

参考文献

Hardegger; Plattner; Blank
Helvetica Chimica Acta, 1944 , vol. 27, p. 793,796